Laser Eye Surgery

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... Can eye disease be staved off with a cancer drug?

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Sam Whiting Sunday, March 26, 2006 Printable Version Email This Article For a guy about to take a needle to the eyeball, David Pratt was in good cheer the other day at San Francisco's West Coast Retina.

"The thought is a lot worse than the actual injection," says Pratt, struggling not to let it get the best of him.

"The thought is awful." He'll have an hour with it while getting his left eye examined before Dr.

Robert Johnson comes in with a syringe of Avastin, which would come as a surprise to anyone who follows biotech news.

Avastin is a much-publicized drug for cancer.

As an unexpected and untested side benefit it also helps eyesight in people with macular degeneration, an age-related disease that is the leading cause of blindness in people over 50.

"This is the first application of a drug that we can expect will improve vision in about one-third of people with the wet stage of macular degeneration," Johnson says.

"All the other treatments are just to slow down the decline in clarity of vision." The use of Avastin for wet macular degeneration is experimental and off-label, meaning it is not FDA approved and there have been no studies to gauge possible adverse effects.

Genentech, which developed Avastin, does no...

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March 25, 2006 I'm seriously considering going to one of those laser eye-surgery places.Right now I have the eyesight of an umpire, or a bat.Actually, I wish I had the eyesight of a bat.

At least bats can drive at night.The reason I'd like to get my eyes overhauled is because I'm tired of wearing glasses.I didn't start needing glasses until I was an adult.I went through the usual stages:Arms suddenly weren't long enough.Squinting didn't work anymore.Drugstore reading glasses.Stronger drugstore reading glasses.Multiple pairs of drugstore reading glasses.Buying drugstore reading glasses by the dozen at Job Lot.

Strategically placing drugstore reading glasses all over the house, in the car, at work.N...