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... Eye and Vision > Gene Variant, Smoking Combine To Increase Macular Degeneration Risk .tcheader { background-color:#94ABBE; border-bottom:#003399 solid 1px; border-right:#003399 solid 1px; border-left:#99ccff solid 1px; border-top:#99ccff solid 1px; color:white; font-family:arial,helvetica,sans-serif; font-size:11px; font-weight:bold; letter-spacing: .5pt; padding:1px; padding-left: 1px; text-decoration:none; display: block; } body{ font-size: 12px; color: #000000; font-family: verdana,arial,helvetica,sans-serif; margin-top: 4px; margin-left: 4px; } a:link { text-decoration: none; } a:visited { text-decoration: none; } a:hover { text-decoration: underline; } Home Aging Eye and Vision Gene Variant, Smoking Combine To Increase Macular Degeneration Risk By: DukeMed News on Mar 07 2006 15:57:56 Macular Degeneration RiskAn interaction between cigarette smoking and a susceptibility gene, called LOC387715, greatly increases the risk of developing age-related macular degeneration (AMD), Duke University Medical Center and Vanderbilt University Medical Center have found.The combination of these factors accounts for as many as one third of the cases of age-related macular degeneration, the researchers estimated.

The study represents one of the first examples of an interaction between genetic and environmental factors in the development of a common disease, they said.The researchers said their findings emphasize the importance of genetic factors in the...

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